Evidence map›Paper›PMID 41082396›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

RiboMicrobe: An Integrated Translatome Atlas for Microorganism.

Yingshun Zhou, Jinjing Luo, Xiaoqiang Lang, Yuli Gan, Guoxian Liu, Yuling Cui, Fazhi Li, Weicong Zhu, Bing Chen, Yuanyuan Dong and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. RiboMicrobe: An Integrated Translatome Atlas for Microorganism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yingshun ZhouDepartment of Pathogenic Biology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, P. R. China.
Jinjing LuoDepartment of Pathogenic Biology, School of Basic Medical Sciences, Southwest Medical University, Luzhou, 646000, P. R. China.
Xiaoqiang LangRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Yuli GanRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Guoxian LiuRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Yuling CuiRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Fazhi LiRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Weicong ZhuRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.
Bing ChenCollege of Life Science, Hebei University, Baoding, 071002, P. R. China.
Yuanyuan DongCollege of Life Sciences, Jilin Agricultural University, Changchun, Jilin, 130118, P. R. China.
Yinglin WuSchool of Life Science and Technology, Lingnan Normal University, Zhanjiang, Guangdong, 524048, P. R. China.
Yi CaoMicrobiology and intelligent biomanufacturing Key Laboratory of Sichuan Province, College of Life Science, Sichuan University, Chengdu, Sichuan, 610041, P. R. China.
Qi LiuRice Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou, 510640, P. R. China.ORCID https://orcid.org/0009-0009-2514-9294

Funding

Elite Rice Plan of GDRRI 2022YG01Jinying's Light Plan of GADDS R2023PY-JG001Luzhou Science and Technology Bureau and Southwest Medical University 2024LZXNYDT003National Natural Science Foundation of China 32270698National Natural Science Foundation of China 32271535Sichuan Province Science and Technology 2022YFS0631Sichuan Province Science and Technology 2025ZNSFSC0677
6 · The paper itself

Abstract

Ribosome profiling (Ribo-seq) represents a significant advance in translatomics research. This technique enables the precise measurement of global and in vivo translation dynamics, the quantification of translation, and the identification of active translated small open reading frames (sORFs). While several databases have been developed to focus on the translatome, comprehensive databases dedicated specifically to analyses of translation and sORFs in prokaryotes remain scarce. Therefore, RiboMicrobe (https://rnainformatics.org.cn/RiboMicrobe/ and https://rnainformatics.cn/RiboMicrobe/) develops a comprehensive database tailored for Ribo-seq data from prokaryotic microorganisms, Accompanying this database, it also introduces two novel sORF prediction models based on transformer-based deep learning architecture, sORFPredRibo and sORFPred, to support translatomics analyses and sORF annotation. Currently, RiboMicrobe encompasses 891 Ribo-seq, 369 matched RNA-seq, and 62 proteome datasets from 36 prokaryotes and 2 viruses, and provides users with intuitive web interfaces to easily access and explore information of interest. In addition, a suite of bioinformatics tools encompassing three functional categories: visualization tools (Browse, JBrowse, and mRNABrowse) is developed for data exploration; predictive algorithms (sORFPred and sORFPredRibo) for sORFs prediction; and comparative analysis utilities (DiffTE, DiffCO, and BLAST) for functional investigations. It is believed that the diverse data and capabilities of RiboMicrobe will advance the field of microbial translational research substantially.

Indexed as

Computational BiologyProtein BiosynthesisRibosomesBacteriaDatabases, GeneticOpen Reading FramespredictionprokaryotesRiboMicroberibosome profilingsORFtranslatomics

Identifiers

PMID41082396
PMCPMC12752654

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.