Evidence map›Paper›PMID 41082128›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Brain connectivity changes associated with acute sleep deprivation: a systematic review.

Stephanie Hosang, Karen Wong, Daniella Mlinarevic, Brian Krivoruk, Hiruthika Ravi, Darren Hamilton, Loretta Norton, Bobby Stojanoski, Saptharishi Lalgudi Ganesan

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephanie HosangDepartment of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Karen WongDepartment of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Daniella MlinarevicSchulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Brian KrivorukDepartment of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Hiruthika RaviDepartment of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada.
Darren HamiltonHealth Sciences Library, London Health Sciences Centre, Health Disciplines, London, ON, Canada.
Loretta NortonDepartment of Psychology, King's University College, London, ON, Canada.
Bobby StojanoskiWestern Institute for Neurosciences (WIN), Western University, London, ON, Canada.
Saptharishi Lalgudi GanesanDepartment of Paediatrics, Schulich School of Medicine & Dentistry, Western University, London, ON, Canada. rishi.ganesan@lhsc.on.ca.ORCID http://orcid.org/0000-0002-2599-9119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesSleep deprivation related changes in brain connectivity have been poorly characterized but have important implications for delirium patients and shift workers. This study aimed to describe the functional and effective brain connectivity changes after acute sleep deprivation (ASD).

methodsA systematic search of OvidSP Embase, PubMed, and Web of Science databases was conducted for studies published between January 1, 1947, to September 11, 2024. Selected studies examined brain connectivity strength or topology, estimated by electroencephalography, functional magnetic resonance imaging, functional near-infrared spectroscopy, magnetoencephalography, or positron emission tomography, after ASD. Data extracted from eligible studies included primary outcomes: functional neuroimaging modality, type of brain connectivity analyses and results of brain connectivity analyses. Studies were grouped for synthesis based on functional neuroimaging modality and connectivity measures.

resultsThe search produced 1015 articles. 357 duplicates were removed, and 658 articles were screened. Of these, 250 underwent full-text review and 141 were excluded. This produced 109 articles for review. Results demonstrated that the methodology and analyses employed to study functional and effective connectivity after ASD were heterogeneous. However, despite this heterogeneity, studies demonstrated that ASD leads to robust and consistent alterations in the functional/effective connectivity of multiple brain networks, particularly the default mode network.

conclusionsThis review summarizes the key functional and effective connectivity changes associated with ASD. This work will serve as a reference and resource for researchers and clinicians focused on delirium and related conditions, in addition to those interested in ASD and shift work.

Indexed as

BrainConnectomeNerve NetSleep DeprivationHumansAcute sleep deprivationBrain networksDeliriumElectroencephalographyFunctional connectivityFunctional magnetic resonance imaging

Identifiers

PMID41082128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.