ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025
A review of MRI signal changes of cerebellar disorders in adults.
Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMRI signal changes in the cerebellum are observed in multiple disorders including vascular diseases, neoplastic lesions, degenerative diseases, inflammatory disorders, metabolic diseases, infections, and trauma. In some diseases, cerebellar involvement is typical and sometimes isolated, while in other diseases cerebellar lesions are only observed occasionally in the presence of other typical extra-cerebellar abnormalities.
methodsIn this review, we will discuss the MRI characteristics of cerebellar lesions in adults observed in disorders with typical or frequent cerebellar involvement.
resultsInterpreting these cerebellar signal changes on MRI is essential to determine the underlying disorder. Assessing the lesion on MRI forms an essential part of diagnosis and follow-up, alongside patient's history, clinical state and other radiological and non-radiological examinations.
conclusionThe interpretation of cerebellar lesions on MRI depends on their exact localisation inside the cerebellum (e.g. uni- or bilateral lesions, involvement of the cerebellar peduncles, subcortical or cortical regions, or the deep cerebellar nuclei), signal changes on different MRI sequences, change of abnormalities over time, and the presence and characteristics of associated MRI lesions outside the cerebellum.
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