ArticleWorld journal of microbiology & biotechnology2025
Genetic diversity and reproductive modes of aflatoxin-producing Aspergillus flavus isolated from cashew nuts in coastal Kenya.
Article in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Cashew (Anacardium occidentale L.) is a major cash crop in the coastal region of Kenya, as a source of livelihood for small-scale farmers in Kilifi, Kwale and Lamu counties. Despite being an important food crop, cashew nuts are highly susceptible to aflatoxin-producing Aspergillus flavus, primarily due to their nutritional profile and poor pre-harvest and post-harvest practices. The presence of aflatoxins poses significant health risks to consumers of cashew nuts due to the carcinogenic, genotoxic, and hepatotoxic nature of these toxins. The detection of aflatoxin-producing Aspergillus flavus in cashew nuts from coastal Kenya demonstrates the necessity for comprehensive research aimed at mitigating the risk of aflatoxicosis outbreaks, which continue to pose a major public health challenge in the country. In this study, we report for the first time the genetic diversity and modes of reproduction of aflatoxigenic A. flavus using genome-wide single-nucleotide polymorphism (SNP) markers. 33,752 bi-allelic SNPs obtained from 17 A. flavus isolates from Kilifi, Kwale and Lamu counties were used. Our analyses revealed a lack of differentiation and low genetic diversity among A. flavus populations from cashew nuts in the coastal region. Both heterothallic and homothallic A. flavus isolates were observed, with heterothallic and MAT1-2 genes being more predominant. Clonal reproduction was evidenced by the unequal distribution of mating type genes and the observed low genetic diversity. Further analysis of the extent of recombination and linkage disequilibrium (LD) found A. flavus population to be sexually recombining, although we hesitate to interpret these results due to the small sample sizes. Our phylogenetic analyses indicated that our populations are likely to produce low levels of aflatoxins. Overall, these findings provide valuable insights into the population genetics of A. flavus, which can inform future research and strategies to mitigate aflatoxin contamination in cashew nuts, ensuring consumer safety and safeguarding the source of income for the people of the coastal region of Kenya.
Indexed as
Identifiers
41082092What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.