Evidence map›Paper›PMID 41081975›Full record

ArticleJournal of robotic surgery2025

The impact of intrathecal analgesia with diamorphine on postoperative recovery in elective robotic-assisted colorectal surgery: a retrospective cohort study.

Shubham Jain, Aravindhdoss Devadoss, Natalie Claridge, Ian Driver, Arshad Malik

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Article in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shubham JainDepartment of General Surgery, Ipswich Hospital, Heath Rd, Ipswich, Suffolk, IP4 5PD, UK.ORCID http://orcid.org/0000-0002-3534-9312
Aravindhdoss DevadossDepartment of General Surgery, Ipswich Hospital, Heath Rd, Ipswich, Suffolk, IP4 5PD, UK.
Natalie ClaridgeDepartment of General Surgery, Ipswich Hospital, Heath Rd, Ipswich, Suffolk, IP4 5PD, UK.
Ian DriverDepartment of Anaesthetics, Ipswich Hospital, Heath Rd, Ipswich, Suffolk, IP4 5PD, UK.
Arshad MalikDepartment of General Surgery, Ipswich Hospital, Heath Rd, Ipswich, Suffolk, IP4 5PD, UK. arshad.malik@esneft.nhs.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enhanced recovery after surgery (ERAS) protocols emphasize multimodal interventions to accelerate recovery. Minimally invasive elective robotic-assisted colorectal surgery is an ideal candidate for ERAS protocols. This study evaluates the role of intrathecal analgesia with diamorphine in optimizing postoperative outcomes, focusing on pain control, length of stay (LOS), and complications. A retrospective cohort study was conducted on 246 patients undergoing elective robotic-assisted colorectal surgeries between July 2021 and November 2024 at two hospitals in a single trust (Hospitals A and B). The patients were grouped based on analgesia type: intrathecal analgesia with diamorphine (IA) [Intervention] and non-intrathecal analgesia (nIA) [control] groups. The primary outcomes included LOS, postoperative pain scores, and opioid consumption. The secondary outcomes were postoperative ileus (POI) and time to first bowel movement. Intrathecal analgesia with diamorphine was used in 61.8% (Hospital A) and 0% (Hospital B) of cases. Patients receiving IA in Hospital A compared to nIA in Hospital A and Hospital B, respectively, had significantly shorter LOS (5.3 days vs. 6.1 days and 7.0 days, p < 0.001), reduced opioid requirements (88% reduction, p < 0.00001), and a lower incidence of POI (3.6% vs. 13.2% and 14.7%, p = 0.02). Time to bowel function recovery was also faster in the IA group (2.6 days vs. 3.0 days in other groups, p = 0.03). Intrathecal analgesia with diamorphine significantly enhances recovery in elective robotic-assisted colorectal surgery, aligning with ERAS objectives. Its integration into routine practice could optimize patient outcomes, reduce complications, and improve resource utilization. Further prospective studies are needed to confirm these findings.

Indexed as

Analgesics, OpioidColorectal SurgeryElective Surgical ProceduresHeroinPostoperative PainRobotic Surgical ProceduresAdultAgedEnhanced Recovery After SurgeryFemaleHumansIleusInjections, SpinalLength of StayMaleMiddle AgedAnalgesics, OpioidHeroinColorectal surgeryDiamorphineERASIntrathecal analgesiaPostoperative recoveryRobotic surgery

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.