Evidence map›Paper›PMID 41081948›Full record

ArticleBrain structure & function2025

Feed-forward inhibitory circuit from the anterior cingulate cortex regulates periaqueductal gray's panic-like responses.

Changwoo Lee, Changsu Woo, Jongseo Kim, Sukwoo Choi, Shin Jung Kang, Kyuhyun Choi, Ki Soon Shin

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Article in Brain structure & function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Changwoo Lee *Department of Biology, Kyung Hee University, Seoul, 02447, Republic of Korea.
Changsu Woo *Department of Biology, Kyung Hee University, Seoul, 02447, Republic of Korea.
Jongseo KimSchool of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Sukwoo ChoiSchool of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, 08826, Republic of Korea.
Shin Jung KangDepartment of Integrative Biosciences and Biotechnology, Sejong University, Seoul, 05006, Republic of Korea.
Kyuhyun ChoiDepartment of Physiology, College of Medicine, Hallym University, Chuncheon-si, 24252, Gangwon-do, Republic of Korea. kyuhyun@hallym.ac.kr.
Ki Soon ShinDepartment of Biology, Kyung Hee University, Seoul, 02447, Republic of Korea. kisoon_shin@khu.ac.kr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Threatening events elicit panic responses characterized by rapid movement, sympathetic arousal, and negative emotions-critical, instantaneous reactions that can determine survival in moments of acute danger. This study elucidates the neural circuit architecture underlying these responses, focusing on projections from the anterior cingulate cortex (ACC) to the dorsolateral periaqueductal gray (dlPAG) in male mice. We demonstrate that a subpopulation of GABAergic neurons (

Indexed as

Neural InhibitionPanicPeriaqueductal GrayAnimalsBehavior, AnimalConditioning, ClassicalFearGABAergic NeuronsGyrus CinguliMaleMiceMice, Inbred C57BLNeural PathwaysOptogeneticsAnterior cingulate cortexFeed-forward inhibitionPanicPeriaqueductal gray

Identifiers

PMID41081948

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.