ArticleArchives of microbiology2025
Biosorption-based decontamination of mercury by Saccharomyces cerevisiae BY4741.
Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Mitochondrial dysfunction and apoptosis-related gene activation induced by combined ethyl acetate fractions of Uncaria sp. and Selaginella doederleinii in Saccharomyces cerevisiae.Molecular biology reports · 2026Article
- Comparative and functional genomics of yeast Pichia kudriavzevii RWT identify potential genes involved in aflatoxin B1 detoxification.Molecular genetics and genomics : MGG · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Mercury is a neurotoxic heavy metal that threatens to human health and ecosystems. This study examinedthe mercury tolerance and biosorption capacity of the GRAS yeast Saccharomyces cerevisiae BY4741 Growth persisted at 100 ppm but was completely inhibited at 200 ppm; thus, the MIC is bracketed between 100 and 200 ppm. Tolerance assays revealed that the strain BY4741 exhibits a minimum inhibitory concentration (MIC) of ≥ 100 ppm for HgCl₂. Cell viability showed a significant decline (p ≤ 0.05) with increasing mercury concentrations, as determined by the Total Plate Count method. Bioinformatic analysis identified detoxification-related genes (YCF1, YAP1, GSH1, URE2) that were upregulated under HgCl₂ exposure, which are involved in glutathione metabolism, transcriptional regulation, vacuolar efflux, redox homeostasis, and metal ion transport. qRT-PCR confirmed selective activation of these genes, with URE2 displaying the highest induction. Biosorption efficiency reached 49.13% after 24 h of contact time, and X-ray mapping confirmed the accumulation of mercury within the S. cerevisiae biomass. These findings highlight the potential application of S. cerevisiae as a microbial biosorbent for mercury in bioremediation strategies.
Indexed as
Identifiers
41081934What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.