ArticleJournal of neural transmission (Vienna, Austria : 1996)2025
Understanding cognitive features of cervical dystonia: application of the cerebellar cognitive affective syndrome scale (CCAS-S).
Article in Journal of neural transmission (Vienna, Austria : 1996), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical Dystonia (CD) is now recognized to encompass a constellation of non-motor symptoms, including sensory, cognitive, and psychiatric manifestations, which significantly affect patients' quality of life. Cerebellar dysfunction may affect cognitive and affective processing in CD, mirroring cognitive and affective patterns observed in Cerebellar Cognitive and Affective Syndrome (CCAS). To investigate impairments in cerebellar-dependent cognitive and affective domains in CD patients using the Cerebellar Cognitive and Affective Syndrome scale (CCAS-S), and to analyze the potential relationship between cognitive deficits and clinical features of CD. The CCAS-S was administered to twenty CD patients and twenty controls (HC) matched for age, gender, level of education, and MMSE score. For CD patients, disease severity and disability were evaluated using the Toronto Western Spasmodic Torticollis Rating Scales (TWSTRS), while tremor was assessed through the Fahn-Tolosa-Marin Clinical Rating Scale for Tremor (FTM). CD exhibited a significantly lower total CCAS-S score, and a higher number of failed items compared to HC, with marked deficits in specific sub-items such as fluency, delayed verbal recall, similarities, and affective domain. The total number of failed tests revealed high predictive ability (AUC = 0.90), with no significant correlations between disease duration, clinical outcomes, and CCAS-S performance. The CCAS-S is a sensitive screening tool in differentiating cognitive performance in CD and HC, showing a critical cerebellar involvement in the cognitive and affective symptoms of dystonia.
Indexed as
Identifiers
41081874What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.