Evidence map›Paper›PMID 41081859›Full record

Observational studyNeuroradiology2025

Computed tomography-derived K

Jakob Meglič, Katarina Šurlan Popović, Fajko F Bajrović, Primož Gradišek, Jasna Rapnik, Jernej Avsenik

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jakob MegličClinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia. jakob.meglic@kclj.si.
Katarina Šurlan PopovićClinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Fajko F BajrovićInstitute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Primož GradišekDepartment of Anaesthesiology with Reanimatology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Jasna RapnikKirurgija Bitenc, Golnik, Slovenia.
Jernej AvsenikClinical Institute of Radiology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Funding

University Medical Centre Ljubljana 20150039
6 · The paper itself

Abstract

purposeTraumatic brain injury (TBI) often leads to blood-brain barrier (BBB) disruption, contributing to secondary brain damage. Perfusion computed tomography (PCT) may assess BBB permeability through the transfer constant (K

methodsThis observational study included 26 adult patients with moderate or severe TBI. PCT was performed 12-24 h after admission to measure K

resultsA significant positive correlation was found between both initial and peak serum S100B concentrations and mean K

conclusionsOur findings demonstrated a significant correlation between pericontusional K

Indexed as

Blood-Brain BarrierBrain Injuries, TraumaticS100 Calcium Binding Protein beta SubunitTomography, X-Ray ComputedAdultAgedBiomarkersContrast MediaFemaleHumansMaleMiddle AgedBiomarkersContrast MediaS100B protein, humanS100 Calcium Binding Protein beta SubunitBlood-brain barrierPerfusion computed tomographyPermeability imagingSerum S100B

Identifiers

PMID41081859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.