Evidence map›Paper›PMID 41081727›Full record

ArticleBriefings in bioinformatics2025

Microllm: a structured information extraction tool using large language models and named entity recognition in microbiology.

Jing Lu, Fei Li, Lei Feng, Zhengyu Yu, Jianyu Lu, Mingyuan Qin, Shengnan She, Haoqiang Jiang, Zhiming Guo, Jingjing Xia and 1 more

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jing LuDepartment of Dermatology, Huashan Hospital, School of Life Sciences, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China.
Fei LiGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.
Lei FengGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.
Zhengyu YuGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.
Jianyu LuGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.
Mingyuan QinGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.ORCID 0009-0006-8260-7966
Shengnan SheDepartment of Dermatology, Huashan Hospital, School of Life Sciences, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China.
Haoqiang JiangDepartment of Dermatology, Huashan Hospital, School of Life Sciences, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China.
Zhiming GuoGreater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences, Fudan University, 2 Nanjiang Road, Guangzhou 511458, China.
Jingjing XiaDepartment of Dermatology, Huashan Hospital, School of Life Sciences, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China.
Lianyi HanDepartment of Dermatology, Huashan Hospital, School of Life Sciences, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China.ORCID 0000-0002-6364-7843

Funding

Clinical Research Plan of SHDC SHDC22025306Key Specialty Research Centre of Shanghai Health Commission 2023ZZ02018National Key Research and Development Program of China 2025YFC3508403Shanghai Municipal Key Clinical Specialty shslczdzk01002
6 · The paper itself

Abstract

Understanding the characteristics of individual microorganisms is crucial for deciphering microbial community structures and enabling effective system manipulation. Large-scale analysis in microbial bioinformatics is hindered by the scarcity of high-quality annotated datasets, the labor-intensive, and time-consuming process of manual review, and the limitations of current natural language processing (NLP) technologies in effectively capturing comprehensive information. To tackle these challenges, we developed a new tool MicroLLM, which integrates fine-tuned large language models (LLMs) and bidirectional encoder representations from Transformers (BERT) to enhance the extraction of microbial phenotypic information. MicroLLM converts unstructured text into structured JSON objects, making the data more accessible and organized. By leveraging the strengths of LLMs and named entity recognition (NER), it efficiently extracts complex, multirelational, and multi-entity information. This method establishes a strong foundation for constructing large-scale structured knowledge bases, streamlining the creation of scientific knowledge, and advancing our understanding of microbial ecosystems and their impacts on health.

Indexed as

Computational BiologyData MiningMicrobiologyNatural Language ProcessingSoftwareLarge Language Modelshallucination reductionlarge language modelsmicrobial information extractionnamed entity recognitionrelation extraction

Identifiers

PMID41081727
PMCPMC12516959

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.