Evidence map›Paper›PMID 41081584›Full record

ArticleAging2025

Developmental arrest rate of an embryo cohort correlates with advancing reproductive age, but not with the aneuploidy rate of the resulting blastocysts in good prognosis patients: a study of 25,974 embryos.

Andres Reig, Emre Seli

Abstract read
In one paragraph

Article in Aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andres ReigIVIRMA Global Research Alliance, IVIRMA New Jersey, Basking Ridge, NJ 07920, USA.
Emre SeliIVIRMA Global Research Alliance, IVIRMA New Jersey, Basking Ridge, NJ 07920, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the extent to which developmental arrest rate in embryos generated using assisted reproduction correlate with female age and the rate of aneuploidy in the cohort. A total of 25,974 embryos from 1,928 cohorts were included in the study, with an overall embryo developmental arrest (EDA) rate of 40.3% (95% CI: 39.8-40.9%). The median EDA rate increased with age: 33.0% (IQR: 22.0-50-0%) in <35 years old, 38.0% (25.0-50.0%) in 35-37 years old, 40.0% (29.0-54.0%) in 38-40 years old, 44.0% (38.8-56.5%) in 41-42 years old, and 44.0% (40.0-58.0%) in >42 years old;

Indexed as

AneuploidyBlastocystEmbryonic DevelopmentAdultAge FactorsCohort StudiesEmbryo TransferFemaleHumansMaternal AgePregnancyPrognosisdevelopmental arrestembryonic aneuploidyembryonic arrestovarian agingreproductive aging

Identifiers

PMID41081584
PMCPMC12606960

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.