Evidence map›Paper›PMID 41081526›Full record

ArticlemBio2025

Alpha-toxin-elicited CX

Srikanth Mairpady Shambat, Puran Chen, Rocky M Barilla, Markus Huemer, Johanna Snäll, Amanda Welin, Taylor S Cohen, Virginia Takahashi, Samuel B Berry, Alejandro Gómez-Mejia and 11 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Virulence · 2026
    Article
  2. Microbiome Profiling Reveals Prognostic Heterogeneity inmedRxiv : the preprint server for health sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Srikanth Mairpady ShambatCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.ORCID 0000-0002-0527-3978
Puran ChenCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Rocky M BarillaCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Markus HuemerDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-4308-1619
Johanna SnällCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Amanda WelinInstitute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
Taylor S CohenVaccines and Immune Therapies, AstraZeneca, Gaithersburg, Maryland, USA.
Virginia TakahashiVaccines and Immune Therapies, AstraZeneca, Gaithersburg, Maryland, USA.
Samuel B BerryCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Alejandro Gómez-MejiaDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-7313-7169
Tiziano A SchweizerDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Danen M CunoosamyDepartment of Respiratory, Inflammation and Autoimmunity, AstraZeneca, Gothenburg, Sweden.
Sara CajanderDepartment of Infectious Diseases, Faculty of Medicine, and Health, Örebro University, Örebro, Sweden.
Magda LourdaCenter for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.
Volkan ÖzenciDepartment of Clinical Microbiology, Karolinska University Hospital, Huddinge, Sweden.
Ewerton Marques MaggioDepartment of Pathology and Molecular Pathology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Reto A SchüpbachInstitute of Intensive Care, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Kristoffer StrålinDivision of Infection and Dermatology, Department of Medicine Huddinge, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0002-8801-3169
Annelies S ZinkernagelDepartment of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-4700-1118
Anna Norrby-Teglund *Center for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.ORCID 0000-0001-9372-1795
Mattias Svensson *Center for Infectious Medicine, Department of Medicine, ANA Futura, Karolinska Institutet, Karolinska University Hospital, Huddinge, Sweden.ORCID 0000-0003-1695-7934

Funding

BarncancerfondenClinical Research Priority Program (CRPP) of the University of ZurichKarolinska InstitutetNordForsk 90456 PerAIDSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 31003A_176252Svenska Sällskapet för Medicinsk Forskning P17-0179Uniscientia StiftungVetenskapsrådetVetenskapsrådet 2018-151 PerMITVetenskapsrådet 521-2014-6722, 2023-03056_3
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsChemokine CX3CL1Hemolysin ProteinsMonocytesPneumonia, StaphylococcalStaphylococcus aureusADAM10 ProteinAmyloid Precursor Protein SecretasesHumansLungMembrane ProteinsPhagocytosisADAM10 ProteinADAM10 protein, humanAmyloid Precursor Protein SecretasesBacterial ToxinsChemokine CX3CL1CX3CL1 protein, humanHemolysin ProteinsMembrane Proteinsstaphylococcal alpha-toxinADAM10chemotaxisCX3CL1fractalkinemonocytespneumoniaStaphylococcus aureusα-toxin

Identifiers

PMID41081526
PMCPMC12607776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.