Evidence map›Paper›PMID 41081390›Full record

ArticleMicrobiology spectrum2025

Activity of cefiderocol against

John H Kimbrough, Maura H Karr, Sean T Nguyen, Boudewijn L M DeJonge, Chris Longshaw, Miki Takemura, Yoshinori Yamano, Mariana Castanheira, Rodrigo E Mendes

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Performance evaluation of antimicrobial susceptibility testing methods for ceftazidime-avibactam and imipenem-relebactam against Klebsiella pneumoniae and Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. Cefiderocol nonsusceptibility among carbapenem-resistantAntimicrobial agents and chemotherapy · 2026
    Article
  4. ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  5. Challenges and opportunities in the management of severe pneumonia. Key concepts from the Seventh Annual Meeting of Spanish Experts 2025.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  6. Review
  7. Mechanisms ofMedicina (Kaunas, Lithuania) · 2026
    Review
  8. Metallo-β-lactamase-producingFrontiers in microbiology · 2026
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

John H KimbroughElement Iowa City (JMI Laboratories), North Liberty, Iowa, USA.ORCID 0000-0002-0457-1543
Maura H KarrElement Iowa City (JMI Laboratories), North Liberty, Iowa, USA.
Sean T NguyenShionogi Inc., Florham Park, New Jersey, USA.
Boudewijn L M DeJongeShionogi Inc., Florham Park, New Jersey, USA.ORCID 0000-0002-8647-6274
Chris LongshawShionogi B.V., London, United Kingdom.ORCID 0000-0002-5586-7256
Miki TakemuraShionogi & Co., Ltd., Osaka, Japan.ORCID 0000-0002-1949-5555
Yoshinori YamanoShionogi & Co., Ltd., Osaka, Japan.
Mariana CastanheiraElement Iowa City (JMI Laboratories), North Liberty, Iowa, USA.ORCID 0000-0003-0126-1782
Rodrigo E MendesElement Iowa City (JMI Laboratories), North Liberty, Iowa, USA.ORCID 0000-0002-8648-1137

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cefiderocol and the β-lactam/β-lactamase inhibitor (BL-BLI) combinations ceftazidime-avibactam (CAZ-AVI), imipenem-relebactam (IMI-REL), and ceftolozane-tazobactam (TOL-TAZ) are recommended for the treatment of difficult-to-treat resistance (DTR)

Indexed as

Anti-Bacterial Agentsbeta-Lactamase InhibitorsCephalosporinsPseudomonas aeruginosaPseudomonas InfectionsAzabicyclo Compoundsbeta-LactamasesCefiderocolCeftazidimeDrug CombinationsDrug Resistance, Multiple, BacterialEuropeHumansMicrobial Sensitivity TestsPhenotypeTazobactamAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo Compoundsbeta-Lactamase Inhibitorsbeta-LactamasesCefiderocolCeftazidimeceftolozane, tazobactam drug combinationCephalosporinsDrug CombinationsrelebactamTazobactamcarbapenem resistanceDTRguidelinesIDSAMBL

Identifiers

PMID41081390
PMCPMC12584632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.