ArticleThe veterinary quarterly2025
Glucose-6-phosphatase catalytic subunit 3 enhances host resistance to porcine epidemic diarrhea virus through regulating glycolysis/gluconeogenesis.
Article in The veterinary quarterly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Baicalein solid dispersion prepared by solvent evaporation enhances oral bioavailability and alleviates ulcerative colitis.International journal of pharmaceutics: X · 2026Article
- Early-Life Diarrhea Disrupts Antioxidant-Immune Homeostasis and Gut Microbiota in Suckling Calves.Biology · 2026Article
- Porcine epidemic diarrhea virus promotes viral replication via ROS/HIF-1α-mediated glycolysis.Redox biology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Porcine epidemic diarrhea virus (PEDV) causes a highly contagious disease in pigs, and the intricacies of its host-pathogen interactions require further elucidation. Chinese Min piglets, known for their superior resistance to stress and disease, were compared with Yorkshire piglets to investigate breed-specific resistance mechanisms. We established PEDV infection models in both breeds and analyzed differences by assessing cytokine levels, viral loads, and histological changes in jejunal tissues. Transcriptomic analysis of jejunal tissues identified 5422 differentially expressed (DE) protein-coding genes (PCGs) and 1999 DE long non-coding RNAs (lncRNAs) between the two pig breeds. Functional annotation revealed that Yorkshire piglets exhibited upregulation of inflammatory and apoptotic pathways, whereas Chinese Min piglets displayed strong inflammatory responses and enhanced mucosal immunity. Notably, glucose-6-phosphatase catalytic subunit 3 (
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Registered trials
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