ArticleCirculation reports2025
Predictivity of Each Readiness-to-Explant Criterion for Successful Venoarterial Extracorporeal Membrane Oxygenation Explantation.
Article in Circulation reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Inhaled Nitric Oxide During ECPELLA Weaning: Interpreting Pulmonary Artery Pulsatility Index Beyond a Single Number.Circulation reports · 2026Article
- Inhaled Nitric Oxide Therapy and Changes in Pulmonary Artery Pulsatility Index During Venoarterial Extracorporeal Membrane Oxygenation Weaning in Cardiogenic Shock Requiring ECPELLA.Circulation reports · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The use of temporary mechanical circulatory support (tMCS) has revolutionized the management of cardiogenic shock (CS). However, standardized readiness-to-explant criteria for venoarterial extracorporeal membrane oxygenation (VA-ECMO) have not been established. Methods and Results: We performed a retrospective analysis of 37 patients with CS who were explanted from VA-ECMO at Okayama University Hospital from December 2018 to May 2024 to evaluate the diagnostic performance of each readiness-to-explant criterion for explant success or failure. Explant success was defined as 30-day survival without re-insertion of MCS. Hemodynamic parameters were assessed at explant, weaning (1.0 to 1.5 L/min), and the off test (5 min). We assessed the predictive performance among parameters in successful or unsuccessful explantation of VA-ECMO using receiver operative characteristic curve analysis. The pulmonary artery catheter (PAC) criteria (pulmonary artery wedge pressure ≤18 mmHg, central venous pressure ≤12 mmHg, and cardiac index ≥2.2 L/min/m Conclusions: Our results suggest that the PAC criteria at the off test may be the most appropriate algorithm for predicting successful explantation of VA-ECMO. Further prospective studies are needed to validate the present findings and to establish standardized VA-ECMO explantation practices.
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