Craving mediates the relationship between sleep quality and impaired control over drinking: A preliminary study.

Erica N Grodin, Wave-Ananda Baskerville, Lara A Ray

Abstract read

In one paragraph

Article in Drug and alcohol dependence reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Sleep disturbance is associated with greater subjective and neural negative emotionality in people with alcohol use disorder.Drug and alcohol dependence · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erica N GrodinDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA.

Wave-Ananda BaskervilleDepartment of Psychology, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Lara A RayDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA 90095, USA.

Funding

Characterizing the Microbiome-Gut-Brain Axis in Individuals with Alcohol Use DisorderK01AA029712 · NIAAA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Erica N Grodin · 2022 to 2026

$819k

NIAAA NIH HHS K01 AA029712

6 · The paper itself

Abstract

Background: Sleep disturbances are common in individuals with alcohol use disorder (AUD). Craving is a critical driver of alcohol use and return to drinking and is influenced by sleep. Craving may be a mechanism underlying the relationship between sleep disturbance and alcohol use, such that sleep disturbances result in higher craving, limiting control over alcohol use. This study examined craving as a mediator of the relationship between global sleep quality and impaired control over alcohol use. Methods: Sixty-two (35M/27F) individuals with moderate-to-severe AUD participated in the study. Participants reported on past month sleep quality, craving for alcohol, impaired control over alcohol, and confidence to resist drinking in situations commonly precipitating alcohol use. Mediation models were conducted to evaluate craving as a mediator of the relationship between sleep quality and control over alcohol use. Results: There was a significant indirect effect of craving on the relationship between sleep quality and failed control over drinking; confidence to resist drinking in negative affect situations, and confidence to resist drinking in social conflict situations. Conclusion: Craving may be a mechanism through which sleep disturbances increase alcohol use. It is plausible that sleep disturbances reduce the ability for self-regulation, resulting in higher levels of craving and impaired ability to control alcohol use.

Indexed as

Alcohol use disorderCravingImpaired controlSituational confidenceSleep quality

Identifiers

PMID41081244

DOI10.1016/j.dadr.2025.100384

PMCPMC12509111

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.