Evidence map›Paper›PMID 41081090›Full record

ReviewPeerJ2025

Comparison of animal models for immune premature ovarian insufficiency.

Anchun Hu, Yanli Mu, Guanyou Huang, Shuyun Zhao

Abstract readReviewComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Review in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anchun Hu *Reproductive Medicine Center, Xingyi People's Hospital, Qianxina Prefecture, Guizhou, China.
Yanli Mu *Department of Obstetrics and Gynecology, School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Guanyou HuangDepartment of Obstetrics and Gynecology, School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.
Shuyun ZhaoDepartment of Obstetrics and Gynecology, School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Premature ovarian insufficiency (POI) severely impacts women's reproductive and overall health, yet effective treatments remain elusive. Research on its pathogenic mechanisms and therapeutic strategies is therefore critical. Due to the scarcity of ovarian samples from POI patients, animal models have become indispensable tools for investigation. Notably, immune-related POI accounts for an increasing proportion of cases, with over half of idiopathic POI cases hypothesized to involve immune dysregulation. Consequently, immune-mediated POI animal models are widely used to study immune-related mechanisms. This article compares the advantages, limitations, and applications of various immune-related POI animal models, aiming to guide researchers in selecting the most appropriate model for their specific research goals and experimental designs.

Indexed as

Disease Models, AnimalPrimary Ovarian InsufficiencyAnimalsFemaleHumansMiceAnimal modelImmunityOvarian functionPremature ovarian insufficiency

Identifiers

PMID41081090
PMCPMC12513378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.