Evidence map›Paper›PMID 41081083›Full record

ArticleOptica2025

Ultrasensitive Alzheimer's disease biomarker detection with nanopillar photonic crystal biosensors.

Guilherme S Arruda, Katie Morris, Augusto Martins, Yue Wang, Sian Sloan-Dennison, Duncan Graham, Steven D Quinn, Emiliano R Martins, Thomas F Krauss

Abstract read
In one paragraph

Article in Optica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Guilherme S ArrudaSão Carlos School of Engineering, Department of Electrical and Computer Engineering, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID https://orcid.org/0000-0002-5487-0154
Katie MorrisSchool of Physics, Engineering and Technology, University of York, York YO10 5DD, UK.ORCID https://orcid.org/0000-0002-8944-2264
Augusto MartinsSchool of Physics, Engineering and Technology, University of York, York YO10 5DD, UK.ORCID https://orcid.org/0000-0002-9554-6481
Yue WangSchool of Physics, Engineering and Technology, University of York, York YO10 5DD, UK.ORCID https://orcid.org/0000-0002-2482-005X
Sian Sloan-DennisonDepartment of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre, Glasgow G1 1RD, UK.
Duncan GrahamDepartment of Pure and Applied Chemistry, University of Strathclyde, Technology and Innovation Centre, Glasgow G1 1RD, UK.
Steven D QuinnSchool of Physics, Engineering and Technology, University of York, York YO10 5DD, UK.
Emiliano R MartinsSão Carlos School of Engineering, Department of Electrical and Computer Engineering, University of São Paulo, São Carlos, SP 13566-590, Brazil.ORCID https://orcid.org/0000-0002-6255-1479
Thomas F KraussSchool of Physics, Engineering and Technology, University of York, York YO10 5DD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent development of drugs able to mitigate neurodegenerative diseases has created an urgent need for biomarker tests that can be readily used by practitioners. Although biomarker detection directly in patients' blood is now possible, low-cost point-of-care tests remain a challenge because relevant biomarkers, especially amyloid-

Identifiers

PMID41081083
PMCPMC12510715

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.