Evidence map›Paper›PMID 41080998›Full record

ArticleAsian bioethics review2025

"Your Tumour Can Save Lives": Re-examining Singapore's Consent Procedures for the Use of De-identified Bio-specimens in Research.

Kylie J Q Heng, Shaun S E Loong, Gini W W Wong, Athena Ham, Aaron D'Sa, Mayank Dalakoti, Roger Foo, Jerry Menikoff

Abstract read
In one paragraph

Article in Asian bioethics review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kylie J Q HengCardiovascular Metabolic Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Shaun S E LoongCardiovascular Metabolic Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Gini W W WongDuke-NUS Medical School, Singapore.
Athena HamUniversity of Cambridge, Cambridge, England UK.
Aaron D'SaUniversity of Cambridge, Cambridge, England UK.
Mayank DalakotiCardiovascular Metabolic Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Roger FooCardiovascular Metabolic Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Jerry MenikoffFaculty of Law, National University of Singapore, Singapore.ORCID 0009-0001-7032-3070

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consent in research is inarguably a highly contentious and debated topic. One of the biggest debates in research ethics revolves around the determination of when consent is necessary, as there is a need to balance participant protections and research advancements. Contrary to popular belief, obtaining informed consent may not necessarily be better for the participant. One illustration of this can be taken from the United States' (US) 2011 proposal to require consent for the research use of de-identified bio-specimens under the applicable regulations (what is often referred to as the "Common Rule"). The proposed transition from no consent to broad consent was met with strong opposition from researchers and the public alike, highlighting the possible superiority of not requiring consent when de-identified bio-specimens are used in research. Against this backdrop, this article uses legal and bioethical perspectives to evaluate Singapore's consent procedures for the secondary research use of de-identified bio-specimens, arguing that Singapore is ready and in need of further liberties to allow for more robust research advancements and better participant outcomes.

Indexed as

Biomedical ethicsConsentDe-identified bio-specimensHuman biomedical researchLawResearch ethics

Identifiers

PMID41080998
PMCPMC12508294

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.