ArticleFrontiers in medicine2025
Sex differences and gender-oriented characteristics in intensive care unit admissions for patients with traumatic brain injury in Spain.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Vascular access in out-of-hospital cardiac arrest with non-shockable rhythms-a retrospective observational study of the intravenous versus intraosseous approach: the VANISH study.Frontiers in public health · 2026Observational
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Authors and funding
12 authors.
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Abstract
Background: Traumatic brain injury (TBI) is a major public health concern with significant mortality, disability, and socioeconomic impact. Previous studies have shown that biological sex influences TBI incidence and outcomes, yet sex-specific data remain underexplored. We aimed to analyze clinical characteristics, resource utilization, and outcomes of ICU-admitted TBI patients in Spain, with a focus on sex-related differences. Material and methods: We performed an observational and retrospective study utilizing data from the RETRAUCI registry, involving 50 registered ICUs and 124 investigators. Patients admitted from March 2015 to December 2019 with isolated significant TBI (AIS ≥ 3) were included. Data on epidemiology, acute management, injury type, resource utilization, complications, and outcomes were recorded. Results: Of the 950 patients, 76% were male. Women had significantly longer ICU stays (11.03 vs. 9.43 days; Conclusion: These findings show that sex significantly influences TBI patterns and in-hospital evolution. Men had higher rates of trauma from risk-related behaviors, while women experienced longer ICU stays and greater psychotropic use. Such differences call for sex-specific approaches in clinical care and further prospective research.
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