Evidence map›Paper›PMID 41080862›Full record

SynthesisFrontiers in public health2025

Dose-response relationship of physical exercise interventions for balance performance in children and adolescents with intellectual disabilities: a systematic review and meta-analysis.

Ziqi Gao, Yafan Li, Yaxin Wang, Wei Quan, Hongnan Meng, Jianxin Kang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ziqi GaoPostgraduate School, Harbin Sport University, Harbin, China.
Yafan LiPostgraduate School, Harbin Sport University, Harbin, China.
Yaxin WangPostgraduate School, Harbin Sport University, Harbin, China.
Wei QuanSchool of Physical Education, Heilongjiang University of Technology, Jixi, China.
Hongnan MengPostgraduate School, Harbin Sport University, Harbin, China.
Jianxin KangPostgraduate School, Harbin Sport University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To systematically evaluate the impact of exercise interventions on balance performance in children and adolescents with intellectual disabilities and examine the dose-response relationship of key intervention parameters. Methods: A comprehensive search of PubMed, Web of Science, Embase, Scopus, and the Cochrane Library identified eligible randomized controlled trials (RCTs). Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Subgroup analyses and non-linear meta-regression were performed to explore potential effect modifiers and dose-response patterns. Results: A total of 23 eligible studies comprising 31 datasets and 1,179 participants were included. Pooled analysis showed significant improvement in balance performance [SMD = 0.69, 95% CI (0.48, 0.89), Conclusion: Moderate-dose exercise (717 MET·min/week) can significantly improve the balance performance in children and adolescents with intellectual disabilities, with specific frequency, duration, and intervention period combinations yielding superior outcomes. These findings provide an evidence-based basis for precision health strategies. However, moderate heterogeneity highlights the need for confirmation through larger, multicenter, and long-term trials.

Indexed as

ExerciseExercise TherapyIntellectual DisabilityPostural BalanceAdolescentChildHumansMaleRandomized Controlled Trials as Topicbalance performancechildren and adolescentsdose–response relationshipexercise interventionintellectual disabilitymeta-analysis

Identifiers

PMID41080862
PMCPMC12507773

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.