ReviewBiochemistry and biophysics reports2025
The role of long intergenic non-protein coding RNA 312 in cancer: A bioinformatics and literature based study.
Review in Biochemistry and biophysics reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
LINC00312 encodes an intronless transcript mainly functioning as a tumor suppressor. Expression of this transcript is downregulated in a variety of cancers, particularly lung cancers. It is regarded as a negative regulator of estrogen receptor signaling. Moreover, low expression of LINC00312 correlates with poor survival in sarcoma and stomach adenocarcinoma, suggesting its potential as a prognostic biomarker. In the current study, we performed a bioinformatics and literature based approach to find the importance of this long non-coding RNA in different cancers, its regulatory network and its interactions with different biomolecules and compounds. Taken together, LINC00312 represents a possible candidate for additional diagnostics and prognostics approaches.
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