Evidence map›Paper›PMID 41080719›Full record

ArticleMaterials today. Bio2025

A biomimetic nanoplatform for endogenous self-replenishing of oxygen to promote sonodynamic therapy for targeted ablation of activated macrophages in atherosclerotic plaques.

Jia Liu, Sijin Chen, Wenli Zhang, Zhongsheng Xu, Yun Liu, Xiyue Rong, Ying Luo, Lian Xu, Junrui Wang, Yi Wang and 5 more

Abstract read
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jia LiuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Sijin ChenDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Wenli ZhangDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Zhongsheng XuChongqing Key Laboratory of Ultrasound Molecular Imaging, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yun LiuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Xiyue RongDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Ying LuoDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Lian XuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Junrui WangDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yi WangDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Qianying DuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Bo LiuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Yu ZhangDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Jie XuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.
Dajing GuoDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis (AS) is a chronic inflammatory condition associated with increased morbidity and mortality. Nanomaterial-based sonodynamic therapy (SDT) shows considerable potential as a noninvasive treatment for AS. The efficacy of SDT is often limited by the unstable generation of reactive oxygen species (ROS) due to inadequate oxygen availability in the cellular microenvironment. In this study, a biomimetic nanoplatform (HMnO

Indexed as

atherosclerosisbiomimetic nanoplatformefferocytosissonodynamic therapy (SDT)

Identifiers

PMID41080719
PMCPMC12510215

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.