ArticleFrontiers in immunology2025
Dectin-1 and dectin-2 drive protection against
Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
3 authors.
Funding
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Abstract
Introduction: The emerging fungal pathogen Methods: Wild-type, Dectin-1 and/or Dectin-2 knockout, and IL-17A/F knockout C57BL/6J mice were challenged with Results: We showed that the receptors are essential for host survival, necessary to limit the fungal dissemination, and that their main effector functions can be related to shaping the T cell response, notably the cytotoxic CD8+ and Treg cell populations, instead of a conventional TH17 profile. While we also observed a contribution of IL-17 in the host defense, the cytokine is not involved in the restriction of the fungal growth. Discussion: Our results uncover dectin-1 and dectin-2 as novel determinants of protection against
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Registered trials
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