Evidence map›Paper›PMID 41080543›Full record

ArticleFrontiers in immunology2025

Essential roles of CTCF binding sites at TAD boundaries in modulating chromatin interactions and transcriptional regulation at the

Kazuya Muto, Daiki Yoshida, Toshiyuki Suzuki, Natsuo Yamamoto, Naokazu Inoue, Akiko Murakami-Sekimata, Ken Iseki, Masayuki Sekimata

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kazuya MutoRadioisotope Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan.
Daiki YoshidaRadioisotope Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan.
Toshiyuki SuzukiRadioisotope Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan.
Natsuo YamamotoSendai City Public Health Center, Miyagi, Japan.
Naokazu InoueDepartment of Cell Science, Institute of Biomedical Sciences, Fukushima Medical University School of Medicine, Fukushima, Japan.
Akiko Murakami-SekimataDepartment of Life Sciences and Nursing, Fukushima Medical University School of Nursing, Fukushima, Japan.
Ken IsekiDepartment of Emergency and Critical Care Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
Masayuki SekimataRadioisotope Research Center, Fukushima Medical University School of Medicine, Fukushima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon-γ (IFN-γ) is a key cytokine essential for host defense and tumor surveillance, and its expression in T cells is tightly regulated by long-range enhancer-promoter interactions within the

Indexed as

CCCTC-Binding FactorChromatinGene Expression RegulationInterferon-gammaAnimalsBinding SitesEnhancer Elements, GeneticMelanoma, ExperimentalMiceMice, Inbred C57BLPromoter Regions, GeneticTh1 CellsTranscription, GeneticCCCTC-Binding FactorChromatinCtcf protein, mouseIFNG protein, mouseInterferon-gammachromatin architectureCTCFenhancerIFN-gintra-TADTADtranscription

Identifiers

PMID41080543
PMCPMC12511032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.