ReviewPhysiology and molecular biology of plants : an international journal of functional plant biology2025
RNA silencing: the future potential strategy for engineering virus resistance in plants.
Review in Physiology and molecular biology of plants : an international journal of functional plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Guest Editorial: Special Issue: "Biology of Plant Viruses and the Resistance Strategies of the Plant Hosts".Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant viruses adversely affect worldwide agriculture and cause immense crop yield losses globally. Scientists have developed various strategies to combat the viral attacks on plants and one such ground-breaking discovery is the RNA interference (RNAi), also known as RNA silencing. RNA silencing has evolved as a major tool for developing viral resistance in plants through gene silencing that involves the intricate use of various small RNAs, such as small interfering RNAs (siRNAs), endogenous microRNAs (miRNAs), artificial miRNAs (amiRNAs), hairpin RNAs (hpRNAs), double-stranded (ds) RNA sprays (topical applications), and the less prevalent short hairpin (sh) RNAs. With tailor-made constructs, RNAi has opened the avenues for the immense potential to down-regulate the desired viral target genes, leading to reduced viral pathogenicity in several crop plants leading to enhanced sustainability in agriculture and food security for the teeming millions across the globe. In this article, we have reviewed the advances made in the generation of virus-resistant plants by using RNAi-based approaches, particularly siRNA- and amiRNA-mediated technologies. Despite certain issues with delivery, specificity, resistance, and safety that impede the RNAi-based treatments, targeted RNA silencing is expected to revolutionize the future agricultural research with tailor-made stress-tolerant crop plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.