ArticlePain reports2025
The effectiveness of a multisite, multidisciplinary analgesic stewardship program: a 12-month retrospective cohort study.
Article in Pain reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
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Abstract
Introduction: Safe and judicious use of opioids is essential for effective pain management and reducing associated harm. Objectives: We examined the effectiveness of a multisite, multidisciplinary analgesic stewardship program comprising of both organisation- and patient-level interventions (intervention) compared with organisation-level interventions alone (control). Methods: This retrospective cohort study included adult inpatients who were either opioid-naïve at preadmission and prescribed a modified-release opioid (opioid-naïve cohort; n = 183) or nonopioid-naïve at preadmission (nonopioid-naïve cohort; n = 577). The primary outcomes were discharge on a modified-release opioid (opioid-naïve cohort), change in oral morphine equivalent daily dose from preadmission to discharge (nonopioid-naïve cohort), and readmission within 2 weeks (both cohorts). Data were collected at preadmission and discharge over 12 months (August 2022 to July 2023). Results: Patients (n = 760, female: 63%) had a mean (SD) age of 71.9 (19.1) years and a hospital length of stay of 11.0 (14.6) days. Among the opioid-naïve cohort, the intervention led to a between-group reduction in discharge on modified-release opioids (OR [95% CI]: 0.23 [0.11-0.49], Conclusion: A multisite, multidisciplinary analgesic stewardship program comprising both organisation- and patient-level interventions may lead to better opioid prescribing at discharge and potentially clinically meaningful reductions in readmission when compared with organisation-level interventions alone.
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