Evidence map›Paper›PMID 41080425›Full record

ArticlePEC innovation2025

Improving medication information systems utilizing a universal design framework.

Kate Li, Grayson Holt, Jeffrey Zabinski, Martin Calabrese

Abstract read
In one paragraph

Article in PEC innovation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kate LiDepartment of Neurosciences, Case Western Reserve University, Cleveland, USA.
Grayson HoltHarvard Medical School, Boston, USA.
Jeffrey ZabinskiDepartment of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Martin CalabreseCenters for Medicare and Medicaid Services, Baltimore, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Almost a quarter of U.S. adults cannot determine what time they should take medication based on instructions printed on prescription medication labels. Taking medication at an incorrect dosage or alongside incompatible foods can lead to severe health complications. Methods: The principles of Universal Design (UD) can guide the design of tools and materials that more effectively communicate medication information to all patients. UD aims to create designs that can be accessed and understood by people of all abilities, ages, and backgrounds. The framework has shown success in several fields, including the built environment, product design, and education. This demonstrated effectiveness suggests UD has the potential to improve the communication of medication information. Results: Applying the evaluative framework identified strengths in perceptible information and flexibility of use across audio aids and digital platforms. However, these tools fail to uphold simple and intuitive use for individuals with low digital health literacy. Applying UD to prescriber-modifiable language can improve simple and intuitive use and tolerance for error, but it encounters limitations in the principles of size and space and low physical effort. These examples highlight the effectiveness of a UD framework in identifying gaps in information access and guiding the creation of more inclusive design approaches. Conclusion: Applying UD principles can address healthcare inequity and create a safer, more reliable medication information system for patients. Innovation: The recent FDA proposal for new Patient Medication Information sheet highlights the need for better communication of medication information. To our knowledge, Universal Design (UD) has not yet been applied to medication information systems. Thus, we propose utilizing Universal Design (UD) as a framework to evaluate and improve medication information systems.

Indexed as

Health literacyMedication adherenceMedication informationUniversal design

Identifiers

PMID41080425
PMCPMC12513261

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.