Evidence map›Paper›PMID 41080402›Full record

ArticleCureus2025

A Case of Progestogen Hypersensitivity: Systemic Allergic Response.

Hannah R Smith, Kyler Stephan, Larry M Fields

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hannah R SmithObstetrics and Gynecology, Lincoln Memorial University DeBusk College of Osteopathic Medicine, Knoxville, USA.
Kyler StephanObstetrics and Gynecology, Lincoln Memorial University DeBusk College of Osteopathic Medicine, Knoxville, USA.
Larry M FieldsObstetrics and Gynecology, Tennova Turkey Creek Medical Center, Knoxville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Progestogen hypersensitivity (PH) is an allergic condition in which women of reproductive age become sensitized to endogenous progesterone and/or exogenous progestins. PH may present as cutaneous manifestations, such as hives, and/or systemic allergic reactions. Allergic flares typically correlate with relative peaks in progesterone during the luteal phase of the menstrual cycle.PH may go unrecognized due to its heterogeneous presentation. In this case report, we discuss a 26-year-old female patient with suspected progestogen hypersensitivity resulting in a monthly systemic allergic response. We also discuss diagnostic factors for PH, pathogenesis, and treatment/management of symptoms.

Indexed as

allergic hypersensitivityprogesteroneprogestinprogestogensystemic allergic conditions

Identifiers

PMID41080402
PMCPMC12513744

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.