Evidence map›Paper›PMID 41080371›Full record

ArticleCureus2025

Spontaneous Cerebrospinal Fluid Otorrhea Secondary to Tegmen Tympani Dehiscence: A Case Report and Literature Review.

Ahmed Hafez Mousa, Badr E Hafiz, Mohammed Aref

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed Hafez MousaNeuroscience, Dubai Health, Dubai, ARE.
Badr E HafizNeurological Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU.
Mohammed ArefNeurological Surgery, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous cerebrospinal fluid (CSF) otorrhea is an uncommon but increasingly recognized condition, particularly in older adults. It most often results from temporal bone defects, such as tegmen tympani dehiscence, which establish abnormal communication between the subarachnoid space and the middle ear or mastoid air cells. Clinical manifestations of CSF otorrhea may range from subtle conductive hearing loss and middle ear effusion to life-threatening recurrent meningitis. High-resolution computed tomography (HRCT) is essential for diagnosis and surgical planning. We are presenting a 66-year-old woman with a history of conservatively managed subdural hematoma, who presented with persistent, clear otorrhea from the left ear. Beta-2 transferrin testing confirmed the presence of CSF. HRCT of the temporal bones demonstrated bilateral tegmen tympani thinning with focal dehiscence, most pronounced on the left, along with a small encephalocele extending into the left mastoid air cells and associated mastoid opacification. Bilateral superior semicircular canal dehiscence was also noted. The patient underwent a left-sided middle cranial fossa approach, which confirmed focal tegmen dehiscence with exposed dura. Postoperatively, the otorrhea resolved, and no intracranial complications occurred. Spontaneous CSF otorrhea secondary to tegmen tympani dehiscence should be considered in older patients presenting with unexplained persistent otorrhea or middle ear effusion. HRCT provides crucial diagnostic information, while the middle cranial fossa approach enables direct repair and durable outcomes. Early recognition and surgical intervention are vital to prevent recurrence and serious complications such as meningitis or hearing loss.

Indexed as

cerebrospinal fluid otorrheaencephalocelemiddle cranial fossa approachsemicircular canal dehiscenceskull base defecttegmen tympani dehiscence

Identifiers

PMID41080371
PMCPMC12510266

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