Evidence map›Paper›PMID 41080315›Full record

ArticleCureus2025

Pharmacist Awareness, Knowledge, and Clinical Engagement of Medication-Related Osteonecrosis of the Jaw: A Survey From a Designated Community Cancer Care Hospital.

Motohiko Sano, Yosuke Iijima, Saya Watanabe, Atsunobu Sagara, Kenta Ushikubo, Miki Yamada, Hiroyuki Ohya, Mashu Morimoto, Norio Horie, Takahiro Kaneko

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Motohiko SanoLaboratory of Clinical Pharmacy Assessment, Hoshi University, Tokyo, JPN.
Yosuke IijimaDepartment of Oral and Maxillofacial Surgery, Saitama Medical University, Saitama, JPN.
Saya WatanabeLaboratory of Clinical Pharmacy Assessment, Hoshi University, Tokyo, JPN.
Atsunobu SagaraDepartment of Pharmacy, Japanese Red Cross Medical Center, Tokyo, JPN.
Kenta UshikuboDepartment of Oral and Maxillofacial Surgery, Saitama Medical University, Saitama, JPN.
Miki YamadaDepartment of Oral and Maxillofacial Surgery, Saitama Medical University, Saitama, JPN.
Hiroyuki OhyaDepartment of Pharmacy Services, Saitama Medical University, Saitama, JPN.
Mashu MorimotoDepartment of Pharmacy Services, Saitama Medical University, Saitama, JPN.
Norio HorieDepartment of Oral and Maxillofacial Surgery, Saitama Medical University, Saitama, JPN.
Takahiro KanekoDepartment of Oral and Maxillofacial Surgery, Saitama Medical University, Saitama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Medication-related osteonecrosis of the jaw (MRONJ) is a clinically challenging condition; however, the actual practice and interprofessional engagement of pharmacists regarding MRONJ remain undetermined. We assessed the awareness, knowledge, and clinical engagement regarding MRONJ among pharmacists working at a cancer care hospital, identified the gaps between theoretical understanding and actual clinical practice, and explored strategies for enhancing interprofessional collaboration and educational support. Methods In this cross-sectional survey, we administered a web-based anonymous questionnaire to 65 pharmacists working at the hospital between February 19 and March 18, 2024. The questionnaire covered topics including pharmacist demographics, clinical experience with bone-modifying agents (BMAs), understanding of MRONJ, and experiences with interprofessional collaborations in dental care. Results Response rate was 78.5% (51/65). Most respondents were in their 20s or 30s (33.3% for both age groups) and had <10 years of professional experience. Approximately 90% were aware of MRONJ; however, only 3.9% had encountered an actual case. Many pharmacists demonstrated an understanding of the link between BMAs and MRONJ; however, only 21.6% reported that they "sometimes" assessed oral conditions during medication counseling, and none reported doing so "always." Notably, 45.1% pharmacists reported difficulties in collaborating with dentists, and overall interprofessional engagement remained limited. Most pharmacists expressed a positive attitude toward interprofessional collaborations, and 98.0% acknowledged the importance of working with dental professionals. However, none had provided oral health information to external dental clinics. Conclusions There is a gap between the theoretical knowledge of MRONJ among pharmacists and their clinical experience. Their limited involvement in outpatient dental care suggests the presence of structural barriers. Interprofessional collaboration and educational support systems need enhancement.

Indexed as

bone-modifying agentscancerinterprofessional collaborationmedication-related osteonecrosis of the jawpharmacistsquestionnaire

Identifiers

PMID41080315
PMCPMC12510792

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.