ArticleCureus2025
Can the Systemic Immune-Inflammation Index Be a Prognostic Factor for Tympanoplasty Success?
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Association between systemic inflammatory markers and otosclerosis: a retrospective case-control study.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective To examine the role of the preoperative systemic immune-inflammation index (SII) in the success of type 1 tympanoplasty. Methods Between 2016 and 2022, 85 out of 442 patients who underwent type 1 tympanoplasty for chronic otitis media (COM) at our clinic met the inclusion criteria. Demographic data, preoperative complete blood count (CBC) results (including the neutrophil-to-lymphocyte ratio (NLR) and SII), audiological test results, computed tomography findings, and six-month follow-up results were evaluated. Results Anatomic outcomes were categorized into two groups based on graft success: Group 1 (64 patients with successful grafting) and Group 2 (21 patients with graft failure), yielding a success rate of 75.3%. Laboratory findings showed no significant differences in hemoglobin, platelet, or lymphocyte values (p>0.05), but neutrophil count (p < 0.05), NLR, and SII values (p < 0.05) were significantly higher in Group 2. The median SII was 509.1 (422.5-596.7) in Group 1 and 609.9 (521.8-790.5) in Group 2. Conclusions In our study, we found a negative correlation between SII, NLR, and type 1 tympanoplasty success. These parameters might be considered new prognostic inflammatory markers for tympanoplasty outcomes.
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