Evidence map›Paper›PMID 41080286›Full record

ReviewCureus2025

Neurobiological Pathways Linking Compulsive Sexual Behavior Disorder and Psychiatric Comorbidities: A Narrative Review.

Agata Puszcz, Jan Górski, Weronika Pierudzka

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Agata PuszczFamily Medicine, University Clinical Hospital, Poznań, POL.
Jan GórskiHospital Medicine, University Clinical Hospital, Poznań, POL.
Weronika PierudzkaHospital Medicine, University Clinical Hospital, Poznań, POL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Compulsive sexual behavior disorder (CSBD) is a newly classified clinical condition characterized by persistent difficulty in controlling sexual impulses, repetitive sexual activity despite adverse consequences, and significant distress or impairment in various life areas. This narrative review explores the clinical and neurobiological overlaps between CSBD and selected mental disorders, including mood and anxiety disorders, attention-deficit/hyperactivity disorder, autism spectrum disorder, obsessive-compulsive disorder, and specific personality disorders. The review emphasizes shared mechanisms, such as dysregulation of the dopaminergic reward system, impairments in emotional regulation, and altered connectivity in brain regions responsible for impulse control and affect processing. Structural and functional neural changes associated with impulsivity, such as abnormalities in the prefrontal cortex, orbitofrontal cortex, and limbic system, are discussed as potential contributors to both CSBD and its comorbid conditions. These findings support a dimensional approach to diagnosis and treatment, highlighting the need for integrated clinical strategies that account for overlapping symptoms and underlying vulnerabilities.

Indexed as

hypersexuality disorderpsychosexual disorderssex addictionssexual compulsivenesssexual dysfunction

Identifiers

PMID41080286
PMCPMC12512434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.