Evidence map›Paper›PMID 41080270›Full record

ArticleCureus2025

Gender-Specific Associations of CYP4F2 (rs1558139) Gene Polymorphism and Serum Levels in Early and Exudative Age-Related Macular Degeneration.

Alvita Vilkeviciute, Rasa Ciumbaraite, Enrika Pileckaite, Loresa Kriauciuniene, Ho Hin Ma, Raimonda Piskiniene, Rasa Liutkeviciene

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alvita VilkeviciuteLaboratory of Ophthalmology, Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.
Rasa CiumbaraiteFaculty of Medicine, Lithuanian University of Health Sciences, Kaunas, LTU.
Enrika PileckaiteLaboratory of Ophthalmology, Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.
Loresa KriauciunieneLaboratory of Ophthalmology, Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.
Ho Hin MaFaculty of Medicine, Lithuanian University of Health Sciences, Kaunas, LTU.
Raimonda PiskinieneDepartment of Ophthalmology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.
Rasa LiutkevicieneLaboratory of Ophthalmology, Neuroscience Institute, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe study aimed to assess the potential association between MATERIALS AND

methodsA total of 204 patients with early AMD, 204 patients with wet AMD, and 294 healthy individuals as controls participated in this study. Genotyping of rs1558139 was carried out using real-time polymerase chain reaction (RT-PCR), while levels of serum CYP4F2 protein were determined by enzyme-linked immunosorbent assay (ELISA).

resultsThe allele A at

conclusionsThe

Indexed as

age-related macular degenerationcyp4f2 serumearly amdexudative amdgene polymorphismrs1558139

Identifiers

PMID41080270
PMCPMC12513538

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