Evidence map›Paper›PMID 41080145›Full record

ArticleFood chemistry: X2025

Ultrasound-assisted deep eutectic solvent extraction versus alkaline extraction: Functional and structural properties of hazelnut proteins.

Esra Kibar Balballi, Gulsah Karabulut

Abstract read
In one paragraph

Article in Food chemistry: X, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Combined Ultrasound and NaHCOFoods (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Esra Kibar BalballiDepartment of Food Engineering, Faculty of Engineering, Sakarya University, Sakarya, 54187, Türkiye.
Gulsah KarabulutDepartment of Food Engineering, Faculty of Engineering, Sakarya University, Sakarya, 54187, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study compared conventional alkaline extraction and ultrasound-assisted deep eutectic solvent (DES-US) extraction for isolating functional proteins from hazelnut meal, an underutilized oilseed by-product. Alkaline extraction at pH 10 achieved the highest protein recovery (260 mg/g) and extraction efficiency (63 %), while DES-US systems yielded moderate soluble recoveries (∼200-220 mg/g) but showed reduced final protein yields (80 mg/g) due to precipitation challenges. Molecular weight profiles confirmed that both methods effectively preserved major storage proteins, including 7S and 11S globulins and 2S albumins. Secondary structural analyses revealed pronounced pH-induced denaturation in alkaline extracts, versus high α-helix retention in DES-US samples (e.g., DES-GLU 95.7 %, DES-SOR 81.6 %). DES-US systems also exhibited higher solubility (75-76 %) compared to alkaline extracts (58-63 %). Emulsifying activity index was significantly higher for DES-US (DES-GLY 15 m

Indexed as

Deep eutectic solventDigestibilityEmulsifying activityHazelnut mealProtein extraction

Identifiers

PMID41080145
PMCPMC12509131

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.