Evidence map›Paper›PMID 41080049›Full record

ArticleFrontiers in pediatrics2025

Bilateral osteochondrosis of the distal tibial epiphysis: a case report and review of the literature.

Victor Aye, Maxime Pilloux, Elio Paris, Dimitri Fasel, Giacomo De Marco, Oscar Vazquez, Christina Steiger, Romain Dayer, Sana Boudabbous, Dimitri Ceroni

Abstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Victor AyeFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Maxime PillouxFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Elio ParisFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Dimitri FaselFaculty of Medicine, University of Geneva, Geneva, Switzerland.
Giacomo De MarcoPediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Oscar VazquezPediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Christina SteigerPediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Romain DayerPediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.
Sana BoudabbousRadiology Department, Geneva University Hospitals, Geneva, Switzerland.
Dimitri CeroniPediatric Orthopedics Unit, Pediatric Surgery Service, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteochondrosis of the distal tibial epiphysis is a rare condition, and its clinical presentation thus remains poorly defined. The few reported cases in the literature suggest an insidious, progressive onset of ankle pain and swelling with no clear history of trauma. Imaging is crucial to diagnosis, with radiographs typically revealing epiphyseal irregularities, fragmentation and sclerosis, whereas magnetic resonance imaging enables the early detection of bone marrow oedema, subchondral fractures and cartilage abnormalities. We report on an 11.5-year-old boy presenting with a history lasting for more than 12 months of left ankle pain and bilateral osteochondrosis of the distal tibial epiphysis. The etiology of distal tibial osteochondrosis remains unclear, with proposed mechanisms including vascular disorders, repetitive microtrauma and genetic predisposition. The condition's rarity, particularly in the bilateral form, suggests a multifactorial pathogenesis going beyond mechanical stress alone. Its prognosis depends on the degree of epiphyseal involvement and the presence of premature physeal closure, emphasizing the importance of early diagnosis and tailored management strategies. Based on this rare case, we summarize more than 75 years of observations of patients with osteochondrosis of the distal tibial epiphysis, discuss its etiology and revise information about its known clinical features, radiological characteristics, pathogenesis and treatment.

Indexed as

bilateraldistal tibia epiphysisosteochondrosispaediatricsportive activity

Identifiers

PMID41080049
PMCPMC12507543

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