ArticleFrontiers in pediatrics2025
The highly accuracy of lymphocyte count in diagnosing influenza A in children during the influenza A season.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To study the value of lymphocyte count in early diagnosis of influenza A in children during the influenza A season. Methods: We selected children aged 0-18 years diagnosed with influenza A who visited the outpatient clinic of Kunming Children's Hospital during the influenza A epidemic in China from March to April 2023 as the case group (influenza group) and matched them with healthy children undergoing physical examinations as the control group. We collected complete complete blood count within 48 h of disease onset in children with influenza A and compared these parameters with those of the control group. Receiver operating characteristic (ROC) curve analysis, restricted cubic spline functions, and decision curve analysis (DCA) were employed to assess diagnostic performance and clinical utility. Results: The results showed that there were 541 children in the influenza group and 597 in the control group, with no statistically significant differences in age and gender distribution between the two groups ( Conclusion: During the influenza A epidemic, a decrease in lymphocyte count within 48 h of onset can serve as an indicator for early detection and diagnosis of pediatric influenza A.
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