Evidence map›Paper›PMID 41079919›Full record

ArticleInternational journal of biological sciences2025

dsHMGB1, released from IL-17A-induced pyroptotic prostate epithelial cells, drives M1 polarization by promoting Pfkp-mediated glycolysis via Jak2/Stat1 transcription in experimental autoimmune prostatitis.

Wenming Ma, Yi Zhang, Wenlong Xu, Yongtao Hu, Weikang Wu, Lei Chen, Li Zhang, Hexi Du, Jialin Meng, Jing Chen and 1 more

Abstract read
In one paragraph

Article in International journal of biological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Involvement of the pyroptosis-HMGB1 axis in systemic diseases.Frontiers in cell and developmental biology · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wenming MaDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Yi ZhangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Wenlong XuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Yongtao HuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Weikang WuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Lei ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Li ZhangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Hexi DuDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Jialin MengDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Jing ChenDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.
Chaozhao LiangDepartment of Urology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HMGB1 ProteinInterleukin-17Janus Kinase 2ProstatitisSTAT1 Transcription FactorAnimalsEpithelial CellsGlycolysisMacrophagesMaleMiceMice, Inbred C57BLProstateHMGB1 ProteinHMGB1 protein, mouseInterleukin-17Jak2 protein, mouseJanus Kinase 2Stat1 protein, mouseSTAT1 Transcription FactorCP/CPPSdsHMGB1glycolysisJak2/Stat1M1 polarization

Identifiers

PMID41079919
PMCPMC12509684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.