Evidence map›Paper›PMID 41079817›Full record

ArticleClinical case reports2025

Amiodarone-Induced Pulmonary Toxicity in an Elderly Patient: A Case Report.

Bal Krishna Subedi, Naveen Gautam, Anuja Upadhyay, Parikshit Chapagain, Daniel Bitetto

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bal Krishna SubediDepartment of Internal Medicine Jefferson Einstein Montgomery Hospital East Norriton Pennsylvania USA.
Naveen GautamDepartment of General Medicine Gulmi Durbar Basic Hospital Gulmi Nepal.ORCID https://orcid.org/0000-0001-6291-333X
Anuja UpadhyayDepartment of Internal Medicine Jefferson Einstein Montgomery Hospital East Norriton Pennsylvania USA.
Parikshit ChapagainDepartment of Internal Medicine AdventHealth Orlando Orlando Florida USA.ORCID https://orcid.org/0000-0002-5161-9706
Daniel BitettoDepartment of Internal Medicine Jefferson Einstein Montgomery Hospital East Norriton Pennsylvania USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amiodarone, a widely utilized and effective class III antiarrhythmic agent, carries a significant risk of severe organ toxicities, notably including the pulmonary system. This report details a case of an 82-year-old female who developed amiodarone-induced pulmonary toxicity (APT) following 2 years of standard 200 mg daily maintenance therapy for atrial fibrillation. The patient presented with progressive dyspnea, non-productive cough, and new-onset oxygen dependency. Diagnostic evaluation, including chest computed tomography revealing diffuse interstitial opacities, alongside the systematic exclusion of other etiologies, confirmed the diagnosis. Prompt discontinuation of amiodarone and initiation of corticosteroid therapy resulted in clinical stabilization. This case underscores the insidious nature of amiodarone-induced adverse effects, particularly in the elderly population, and reinforces the critical necessity for a high index of clinical suspicion and vigilant, proactive monitoring strategies to facilitate early detection and appropriate management of this potentially life-threatening iatrogenic complication, even with standard therapeutic dosages.

Indexed as

adverse drug reactionamiodaroneamiodarone pulmonary toxicityatrial fibrillationcase reportelderly patient

Identifiers

PMID41079817
PMCPMC12513814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.