Evidence map›Paper›PMID 41079725›Full record

ArticleFrontiers in pharmacology2025

Biosynthesized zinc oxide nanoparticles from

Hajar Hassan AlWadai, Shifhali Morabad, Uday M Muddapur, Abdulrahman Manaa Alamri, Bader Aldoah, Adel Moalwi, Nasser A N Alzerwi, Saeed Ali Alsareii, Mater H Mahnashi, Ibrahim Ahmed Shaikh and 2 more

Abstract read
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In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hajar Hassan AlWadaiDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Shifhali MorabadDepartment of Biotechnology, BVB Campus, KLE Technological University, Hubballi, Karnataka, India.
Uday M MuddapurDepartment of Biotechnology, BVB Campus, KLE Technological University, Hubballi, Karnataka, India.
Abdulrahman Manaa AlamriDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Bader AldoahDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Adel MoalwiDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Nasser A N AlzerwiDepartment of Surgery, College of Medicine, Majmaah University, Ministry of Education, Al-Majmaah, Saudi Arabia.
Saeed Ali AlsareiiDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Mater H MahnashiDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Ibrahim Ahmed ShaikhDepartment of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Aejaz Abdullatif KhanDepartment of General Science, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia.
Basheerahmed Abdulaziz MannasahebDepartment of Pharmacy Practice, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Nanotechnology is an innovative approach that involves the development, production, and application of materials via altering their shape and size on the nanometer scale, which ranges from 1 to 100 nm. Zinc Oxide Nanoparticles (ZnONPs) are metal-oxide nanomaterials with distinct physical and chemical properties that make them valuable and adaptable inorganic compounds. Methods: The Results: The surface morphology of the ZnONPs was analyzed using SEM, which revealed their spherical nature and particle size was determined to be 30 nm. Significant peaks were observed in the XRD pattern, confirming their sphere-like structure. FTIR spectra were recorded to determine the groups of biomolecules involved in synthesis. ZnONPs' antibacterial efficacy against gram + ve and gram -ve bacteria, were positive. The ZnONPs demonstrated significant cytotoxic activity against TNBC MDAMB-231 cell line with an IC Discussion: The ZnONPs showed increased cell migration potential in the in vitro scratch assay, highlighting their potential for wound care and tissue regeneration applications. In future, more in-depth research and clinical evaluation are warranted to fully explore the therapeutic potential of these environmentally friendly ZnONPs.

Indexed as

antibacterialanticancerCycas revolutagreen synthesiswound healingzinc oxide nanoparticles

Identifiers

PMID41079725
PMCPMC12507921

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.