ReviewMedComm2025
Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications.
Review in MedComm, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Injectable microsphere-based delivery strategies for stem cells and their derivatives in tissue regeneration.Bioactive materials · 2026Review
- Nanoparticulate and Hydrogel Vehicles for Stimuli-Responsive and Sustained Controlled Release of Active Pharmaceutical Ingredients.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Micro-nano integrated platforms for osteoarthritis therapy: From spatial manipulation to cellular reprogramming.Materials today. Bio · 2026Review
- Hydrogel Microspheres as Versatile Platforms for Biomedical Research: Design, Properties, and Applications.MedComm · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogel microspheres (HMs) are versatile biomaterials with biocompatibility and controlled release properties, widely applied in drug delivery, cell carriers, and tissue engineering. Their tunable material compositions (natural, synthetic, or composite polymers) and diverse fabrication techniques (e.g., microfluidics, electrohydrodynamic spraying) allow precise regulation of size, morphology, and functionality, supporting applications from musculoskeletal repair to dermatological therapy. Despite rapid advancements, a comprehensive understanding of HM design, manufacturing, and biomedical applications is still lacking, as existing reviews mainly focus on single fields or specific scenarios. This review systematically summarizes HMs construction strategies (material selection and property modulation), fabrication technologies (batch emulsion, microfluidic chips, and emerging Artificial Intelligence (AI)-assisted methods), and multifunctional applications (drug and cell delivery, nanoparticle integration, and lubrication modification). It highlights the cross-system therapeutic potential of HMs and discusses challenges in clinical translation. By integrating these aspects, this review aims to bridge the gap between material design and clinical translation, providing researchers with an overview from basic research to clinical application, while exploring approaches to cross-system synergistic therapy and addressing bottlenecks in clinical translation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.