Evidence map›Paper›PMID 41079641›Full record

ArticleJournal of psoriasis and psoriatic arthritis2025

A Trial of Coach-Supported, Smartphone-Delivered Cognitive Behavioral Therapy for Psoriasis With Comorbid Depression.

John S Barbieri, Megan H Noe, Nora Bensellam, Phoebe Holz, Bruna G O Wafae, Ellen Esther Anshelevich, Jasmine N Williams, Ivar Snorrason, Hilary Weingarden, Oliver Harrison and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of psoriasis and psoriatic arthritis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06216691 (Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06216691 nacompletednot on this map

Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms

TypeinterventionalSponsorBrigham and Women's HospitalRan2024 to 2025Enrolled30ConditionsPsoriasis, Depressive SymptomsArmsCoach-guided smartphone delivered CBT program.
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

John S BarbieriDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-5467-4102
Megan H NoeDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Nora BensellamDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Phoebe HolzDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0009-0008-7014-8533
Bruna G O WafaeDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0003-4971-6029
Ellen Esther AnshelevichDepartment of Dermatology, Brigham and Women's Hospital, Boston, MA, USA.
Jasmine N WilliamsDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Ivar SnorrasonDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Hilary WeingardenDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
Oliver HarrisonKoa Health Limited, London, UK.
Sabine WilhelmDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.

Funding

Smartphone-based digital phenotyping to detect high-risk affect states in body dysmorphic disorderK23MH119372 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WEINGARDEN, HILARY · 2019 to 2024
$922k
NIMH NIH HHS K23 MH119372
6 · The paper itself

Abstract

Background: Psoriasis is associated with increased risk of depression. Although cognitive behavioral therapy (CBT) is an evidence-based treatment, access remains limited. Objectives: To evaluate the feasibility, acceptability, and preliminary efficacy of a smartphone-delivered, coach-led CBT program for depression among individuals with psoriasis. Methods: This single-arm, 8-week pilot study (Mindset trial, NCT06216691) enrolled adults with psoriasis and at least mild depressive symptoms (PHQ-9 ≥5). Participants engaged in a smartphone-based CBT program guided by bachelor's-level lay coaches. Primary outcomes were feasibility as evaluated by module completion and acceptability as evaluated by the Client Satisfaction Questionnaire-8 (CSQ-8]) and User Version of the Mobile Application Rating Scale (uMARS). Secondary outcomes included changes in the Patient Health Questionnaire-9 (PHQ-9), General Anxiety Disorder-7 (GAD-7), Appearance Anxiety Inventory, Skindex-16, and Psoriasis Symptom Inventory. Results: Of 30 participants, 63.3% completed ≥4/8 modules and 43.3% completed ≥6/8 modules. Mean CSQ-8 and uMARS scores were 27.2 (SD 4.5) and 4.0 (SD 0.7), respectively, supporting high satisfaction. Statistically and clinically significant improvements were observed in PHQ-9 (mean change -4.4; Cohen's d = 0.92), GAD-7 (-2.8; d = 0.63), and Skindex-16 symptoms (5.0; d = 0.78), emotions (10.0; d = 0.95), and functioning (6.4; Cohen's d = 0.71) subscales as well as the Psoriasis Symptom Inventory (3.1; d = 0.43). Conclusions: This study supports the feasibility, acceptability, and preliminary efficacy of smartphone-delivered CBT for individuals with psoriasis and depressive symptoms. Given the scalability of this model, future randomized trials are warranted to assess broader effectiveness in dermatology care settings.

Indexed as

anxietycoachcognitive behavioral therapydepressionmental healthmobilepsoriasispsoriatic arthritispsoriatic diseasequality of lifesmartphone

Identifiers

PMID41079641
PMCPMC12507800

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.