Evidence map›Paper›PMID 41079637›Full record

ArticleiScience2025

Impact of mycotoxins and glyphosate residue on the gut microbiome and resistome of European fallow deer.

Adrienn Gréta Tóth, Sára Ágnes Nagy, István Lakatos, Norbert Solymosi, Anikó Stágel, Melinda Paholcsek, Katalin Posta, Patrik Gömbös, Szilamér Ferenczi, Zsuzsanna Szőke

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adrienn Gréta TóthCentre for Bioinformatics, University of Veterinary Medicine, 1078 Budapest, Hungary.
Sára Ágnes NagyDepartment of Physics of Complex Systems, Eötvös Loránd University, 1117 Budapest, Hungary.
István LakatosDepartment of Animal Biotechnology, Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, Hungary.
Norbert SolymosiCentre for Bioinformatics, University of Veterinary Medicine, 1078 Budapest, Hungary.
Anikó StágelHungarian National Blood Transfusion Service Nucleic Acid Testing Laboratory, 1113 Budapest, Hungary.
Melinda PaholcsekUniversity of Debrecen Faculty of Agricultural and Food Sciences and Environmental Management, Complex Systems and Microbiome-innovations Centre, 4032 Debrecen, Hungary.
Katalin PostaDepartment of Microbiology and Applied Biotechnology, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, Hungary.
Patrik GömbösAgrobiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Physiology and Nutrition, Department of Physiology and Animal Health, Hungarian University of Agriculture and Life Sciences, 7400 Kaposvár, Hungary.
Szilamér FerencziDepartment of Microbiology and Applied Biotechnology, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, Hungary.
Zsuzsanna SzőkeDepartment of Animal Biotechnology, Agribiotechnology and Precision Breeding for Food Security National Laboratory, Institute of Genetics and Biotechnology, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Some mycotoxins and herbicide residues pose threats to animal health. These toxins might affect the gut microbiome of fallow deer. The analyzation of the intestinal content samples of this valuable game species exposed to varying levels of zearalenone (ZEA) and other toxic compounds such as aflatoxin B1, deoxynivalenol, fumonisin B1, and glyphosate residues was performed. Metagenomic analysis revealed significant alterations in the bacterial community composition. Higher ZEA levels were associated with decreased alpha diversity, whereas higher aflatoxin levels had the opposite effect. Changes in the abundance of antibiotic resistance genes (ARGs) were also observed, suggesting a potential link between mycotoxin exposure and antimicrobial resistance. Furthermore, five complete bacterial genomes were assembled from the metagenomic data. These findings highlight the complex interplay between environmental toxins, gut microbiota, and animal health. Understanding these interactions is crucial for developing strategies to mitigate the negative effects of toxin exposure on wildlife populations.

Indexed as

environmental sciencemicrobiologymicrobiomewildlife microbiologywildlife toxicology

Identifiers

PMID41079637
PMCPMC12514569

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.