Evidence map›Paper›PMID 41079633›Full record

ArticleiScience2025

Urothelial collective-gliding response acts as a toll-like receptor 4-associated defense mechanism.

Ning Zhang, Takeshi Sano, Katsuhiro Ito, Shinji Ito, Ryosuke Ikeuchi, Hideaki Takada, Kenji Nakamura, Toru Sakatani, Akihiro Hamada, Masashi Takeda and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ning ZhangDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takeshi SanoDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Katsuhiro ItoDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shinji ItoMedical Research Support Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ryosuke IkeuchiDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hideaki TakadaDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kenji NakamuraDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Toru SakataniDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Akihiro HamadaDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Masashi TakedaDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kaoru MurakamiDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yuki KitaDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takayuki SumiyoshiDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takayuki GotoDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ryoichi SaitoDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Osamu OgawaDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Michiyuki MatsudaDepartment of Pathology and Biology of Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Takashi KobayashiDepartment of Urology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collective cell migration (CCM) is characterized by the coordinated movement of cell groups while maintaining cell-to-cell cohesion. Despite extensive research on CCM, the collective migration of mature epithelial cells over the extracellular matrix in response to external stimuli has not been reported. Using intravital imaging in mice, we identified urothelial CCM (UCCM) triggered by immunogenic substances, including bladder cancer cells (MB49) and uropathogenic

Indexed as

BiochemistryCell biology

Identifiers

PMID41079633
PMCPMC12508895

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.