Evidence map›Paper›PMID 41079606›Full record

ArticleiScience2025

A recombinant Cedar virus preclinical model that recapitulates neurological features of henipavirus disease.

Celeste Huaman, Caitlyn Clouse, Madeline Rader, Allison M Strazzella, Jocelyn King, Elise M Santorella, Lianying Yan, Shuangyi Bai, Bronwyn M Gunn, Moushimi Amaya and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Celeste HuamanDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Caitlyn ClouseDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Madeline RaderDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Allison M StrazzellaDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Jocelyn KingDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Elise M SantorellaDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Lianying YanDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Shuangyi BaiPaul G. Allen School of Global Health, College of Veterinary Medicine, Washington State University, Pullman WA 99164, USA.
Bronwyn M GunnPaul G. Allen School of Global Health, College of Veterinary Medicine, Washington State University, Pullman WA 99164, USA.
Moushimi AmayaDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Christopher C BroderDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.
Brian C SchaeferDepartment of Microbiology and Immunology, Uniformed Services University, Bethesda, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nipah virus (NiV) and Hendra virus (HeV) are members of the henipavirus genus that cause severe respiratory and/or neurological disease in humans. Because NiV and HeV can only be handled under BSL-4 containment, there are significant practical barriers to the study of pathogenicity and the evaluation of therapeutic countermeasures. However, Cedar virus (CedV) is a non-pathogenic henipavirus that can be used in a BSL-2 setting. Here, we demonstrate that recombinant CedVs that express the F and G glycoproteins of NiV or HeV display an

Indexed as

ImmunologyNeuroscienceVirology

Identifiers

PMID41079606
PMCPMC12510183

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.