ArticleFrontiers in cardiovascular medicine2025
Impact of recipient body mass index on heart transplantation outcomes.
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
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5 authors.
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Abstract
Objective: Obesity is one of the common risk factors for heart failure. Heart transplantation (HTx) is a gold standard treatment option for end-stage heart failure. The relationship between obesity and HTx outcomes is not very clear. This study aims to investigate the impact of recipient BMI on heart transplantation outcomes. Methods: From 2012-2021, 821 patients underwent HTx in our center. Patients with age less than 18 years, multiorgan transplantation, re-transplantation, and missing recipient BMI data were excluded. The remaining 694 patients were divided into four BMI categories based on the recipient's BMI value. BMI < 18.5 kg/m Results: Some preoperative variables, such as recipient gender and diabetes status, were statistically significantly different between the groups. However, there was no significant difference in the postoperative outcomes except for high intra-aortic balloon pump (IABP) use in the BMI ≥ 30 kg/m Conclusion: The recipient BMI did not significantly impact post-transplantation survival after multivariable adjustment. However, unadjusted analyses showed comparable non-survival outcomes across BMI groups. Our study suggests that selected underweight and class I obese patients may undergo heart transplantation without increased risk of post-transplantation mortality.
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