Evidence map›Paper›PMID 41079544›Full record

ArticleResuscitation plus2025

CardioPulmonary resuscitation with

Giuseppe Ristagno, Lidia Staszewsky, Giulia Merigo, Aurora Magliocca, Alberto Cucino, Jennifer Meessen, Francesca Fumagalli, Matteo Pozzi, Alessandro Galazzi, Claudio Sandroni and 17 more

Registry-linked trialAbstract read
In one paragraph

Article in Resuscitation plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05482945 (CardioPulmonary Resuscitation With Argon), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05482945 phase2recruitingnot on this map

CardioPulmonary Resuscitation With Argon (CPAr) Trial

TypeinterventionalSponsorMario Negri Institute for Pharmacological ResearchRan2022 to 2026Enrolled120ConditionsCardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful ResuscitationArmsNoble gas Argon
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Giuseppe RistagnoDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Lidia StaszewskyDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Giulia MerigoDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Aurora MaglioccaDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Alberto CucinoAnaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.
Jennifer MeessenDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Francesca FumagalliDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Matteo PozziSchool of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.
Alessandro GalazziDepartment of Medicine and Surgery, LUM University, Casamassima, Bari, Italy.
Claudio SandroniDepartment of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Rome, Italy.
Marco MeneguzziDepartment of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy.
Anna MarangoneDepartment of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy.
Chiara RobbaIRCCS Policlinico San Martino, Genoa, Italy.
Erik Roman-PognuzDepartment of Medical Science, University of Trieste, Trieste, Italy.
Giovanni SalatiUOC Anestesia e Rianimazione, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.
Edoardo PicettiDepartment of Anaesthesia and Intensive Care, Parma University Hospital, Parma, Italy.
Deborah NovelliDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Giacomo BellaniAnaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.
Mauro PanigadaDepartment of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Lars WikNorwegian National Advisory Unit on Prehospital Emergency Medicine, Division of Prehospital Care, Oslo University Hospital, Oslo, Norway.
Silvio GarattiniIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Giuseppe FotiSchool of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.
Massimo AntonelliDepartment of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario "Agostino Gemelli"-IRCCS, Rome, Italy.
Elisa ZanierDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Giacomo GrasselliDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.
Roberto LatiniDepartment of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
CPAr Study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The CardioPulmonary resuscitation with Argon (CP Methods: CP Conclusion: CP Trial registration: EudraCT-No.: 2018-003047-32; CTIS code: 2024-516864-27-00; ClinicalTrials.gov identifier: NCT05482945.

Indexed as

ArgonCardiac arrestClinical trial protocolInhaled gasesNeuroprotection

Identifiers

PMID41079544
PMCPMC12513211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.