Evidence map›Paper›PMID 41079538›Full record

ArticleKidney medicine2025

The Connection Between Cognitive and Cardiac Function Following Kidney Transplant: The VINTAGE Study.

Sumi Hidaka, Akinori Nishimura, Kazunari Tanabe, Shuzo Kobayashi, VINTAGE Investigators

Abstract read
In one paragraph

Article in Kidney medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sumi HidakaKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Akinori NishimuraRehabilitation Unit, Shonan Kamakura General Hospital, Kanagawa, Japan.
Kazunari TanabeKidney Transplant and Robotic Surgery Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
Shuzo KobayashiKidney Disease and Transplant Center, Shonan Kamakura General Hospital, Kanagawa, Japan.
VINTAGE Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rationale & Objective: The effects of successful kidney transplant (KT) on cognitive function remain unclear. To clarify how the presence or absence of pre-KT mild cognitive impairment (MCI) affects cognitive changes (overall and domain) after KT. To determine whether the cognitive improvement after KT is associated with improved cardiac function. Study Design: A hybrid retrospective and prospective observational cohort study. Setting & Participants: We obtained data from 70 recipients who underwent living donor KT (2017-2021). Predictors: Pre-KT MCI status and left ventricular (LV) remodeling. Outcomes: Changes in mean Montreal cognitive assessment (MoCA) scores before and after KT. Statistical Analysis: We evaluated whether the presence or absence of pre-KT MCI modified the effect of KT (total and each domain). We also evaluated the association between changes in MoCA total score and LV reverse remodeling effect. Results: MoCA total score: no significant change was observed in the non-MCI group (27.6 ± 1.2 to 27.6 ± 1.6, Limitations: Incomplete cerebral blood flow data. Conclusions: The effect of KT was changed by pre-KT MCI status. Heterogeneous cognitive improvement after KT can be explained by the LV reverse remodeling effect.

Indexed as

Cerebral blood flowkidney transplantleft ventricular reverse remodelingmild cognitive impairmentMontreal cognitive assessment

Identifiers

PMID41079538
PMCPMC12510026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.