Evidence map›Paper›PMID 41079492›Full record

ArticleCureus2025

Atypical Postoperative Presentation of Malignant Hyperthermia in an Elderly Patient Following Transcatheter Aortic Valve Replacement.

Matthew W Knick, Benton Nanners, Mir Ali Abbas Khan, Arpan Kohli

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew W KnickAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Benton NannersAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Mir Ali Abbas KhanAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.
Arpan KohliAnesthesiology, West Virginia University School of Medicine, Morgantown, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report an unusual case of an 82-year-old female who developed acute respiratory distress, tachycardia, diaphoresis, and hypertension in the post-anesthesia care unit (PACU) following transcatheter aortic valve replacement (TAVR), which improved significantly after initiation of dantrolene. Given the patient's atypical age, delayed symptom onset, and notable improvement following dantrolene administration, we present an atypical case in which malignant hyperthermia (MH) could not be ruled out based on clinical progression. This case underscores the importance of maintaining a high index of suspicion for MH in atypical presentations and highlights the critical role of timely diagnosis and intervention.

Indexed as

dantrolenehypermetabolic crisismalignant hyperthermiapostoperative complicationstranscatheter aortic valve replacement (tavr)

Identifiers

PMID41079492
PMCPMC12513674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.