Evidence map›Paper›PMID 41079420›Full record

ArticleNature synthesis2025

Synthesis of covalently linked knotted cage frameworks.

Yuchong Yang, Tanya K Ronson, Paula C P Teeuwen, Simone Zucchelli, Andrew W Heard, Paola Posocco, David J Wales, Jonathan R Nitschke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature synthesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Tangled Tail of Mechanically Interlocked Peptides.Journal of the American Chemical Society · 2026
    Review
  2. Review
  3. Hierarchical assembly of a TiNature communications · 2026
    Article
  4. Article
  5. Design and Structural Transformations of Zinc(II) Knotted Cage Frameworks.Angewandte Chemie (International ed. in English) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuchong YangYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0000-0001-9733-3255
Tanya K RonsonYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.
Paula C P TeeuwenYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2571-8161
Simone ZucchelliDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.ORCID 0000-0003-3716-153X
Andrew W HeardYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0000-0002-6815-4618
Paola PosoccoDepartment of Engineering and Architecture, University of Trieste, Trieste, Italy.ORCID 0000-0001-8129-1572
David J WalesYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0000-0002-3555-6645
Jonathan R NitschkeYusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.ORCID 0000-0002-4060-5122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interwoven molecular structures underpin the functions of many biomolecules, yet synthesizing artificial topologically complex structures in high yield remains challenging. Here we describe a streamlined, high-yield one-pot synthesis of knotted cage frameworks by using a subcomponent designed to bridge over the faces of a predesigned cage framework. A Zn

Indexed as

Interlocked moleculesMolecular capsules

Identifiers

PMID41079420
PMCPMC12513843

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.